The Hyve recently added gene set scoring visualization to cBioPortal OncoPrint. To give you an example, we created our own instance that has the TCGA glioblastoma dataset loaded with gene sets identified by Roel Verhaak and colleagues. Using the[…]
Recently the display of germline mutations in the Oncoprint view was developed by The Hyve and has now been added to cbioportal.org. Inherited germline mutations can increase the probability of developing a tumor. This is for example well known for[…]
The OncoPrint view in cBioPortal is a user friendly visualization for genetic alterations. All types of data from a cancer genomic study are integrated in the OncoPrint view: in one overview you can see mutations, expression levels and copy number[…]
One of the key challenges in cancer research is to find patients that will respond well to targeted drug therapy. Specific mutations in a patient’s tumor can be an indication of the patient’s potential responsiveness to such therapy. Recently we[…]
The easiest way to install cBioPortal is using Docker. The Hyve has helped a number of clients in the past with installation of cBioPortal on their infrastructure. By using a Docker image all dependencies for cBioPortal are included, and default[…]
CIViC, a resource for clinical interpretation of cancer variants, was added to cBioPortal by The Hyve. In the decade of precision medicine, accurate and clinically relevant information on variants in cancer patients is extremely important. This[…]
Last week we had the privilege of joining the first cBioPortal hackathon, hosted by Dana Farber Cancer Institute in Boston. The group (with developers from MSKCC, Dana Farber, The Hyve and Princess Margaret Cancer Centre) was divided into four[…]
The cBioPortal for Cancer Genomics is a well known, and well loved, interface for interactive analysis of cancer data. It has been developed, maintained and is also heavily used by the Memorial Sloan Kettering Cancer Center in New York.