Last month we enjoyed the privilege of joining the latest cBioPortal hackathon, this time hosted by MSKCC at the New York Genome Center and counting with the participation of The Hyve, Dana Farber, Princess Margaret Cancer Centre and Children's[…]
The cBioPortal for Cancer Genomics has recently incorporated a new feature developed by The Hyve which allows for visualization of the Fraction of Genome Altered or the Total Mutations in the Plots tab.
The Hyve recently added gene set scoring visualization to cBioPortal OncoPrint. To give you an example, we created our own instance that has the TCGA glioblastoma dataset loaded with gene sets identified by Roel Verhaak and colleagues. Using the[…]
Recently the display of germline mutations in the Oncoprint view was developed by The Hyve and has now been added to cbioportal.org. Inherited germline mutations can increase the probability of developing a tumor. This is for example well known for[…]
The OncoPrint view in cBioPortal is a user friendly visualization for genetic alterations. All types of data from a cancer genomic study are integrated in the OncoPrint view: in one overview you can see mutations, expression levels and copy number[…]
One of the key challenges in cancer research is to find patients that will respond well to targeted drug therapy. Specific mutations in a patient’s tumor can be an indication of the patient’s potential responsiveness to such therapy. Recently we[…]
The easiest way to install cBioPortal is using Docker. The Hyve has helped a number of clients in the past with installation of cBioPortal on their infrastructure. By using a Docker image all dependencies for cBioPortal are included, and default[…]
CIViC, a resource for clinical interpretation of cancer variants, was added to cBioPortal by The Hyve. In the decade of precision medicine, accurate and clinically relevant information on variants in cancer patients is extremely important. This[…]